All research categories

Highlights

  • Enhancing the Cre-loxP system

    Two new genetic tools – roxCre and loxCre – can improve the performance of the Cre-loxP system for making genetic modifications in vivo.

    Mengyang Shi, Jie Li ... Bin Zhou
    Reviewed Preprint Updated

  • Cell mechanics and metastasis

    The discovery of a pro-invasive mechanotransduction pathway driven by cell crowding suggests that an ion channel called TRPV4 may be a promising therapeutic target for inhibiting metastasis.

    Xiangning Bu, Nathanael Ashby ... Inhee Chung
    Reviewed Preprint Updated

  • Science Under Threat in the US

    The new administration in the US is conducting an assault on science and scientists – how should the scientific community respond?

    Collection

Latest research

    1. Neuroscience
    2. Computational and Systems Biology

    Olfactory combinatorial coding supports risk-reward decision making in C. elegans

    Md Zubayer Hossain Saad, William G Ryan ... Bruce A Bamber
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience
    2. Evolutionary Biology

    The first complete 3D reconstruction and morphofunctional mapping of an insect eye

    Anastasia A Makarova, Nicholas J Chua ... Alexey A Polilov
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Genetics and Genomics
    2. Evolutionary Biology

    Fast evolutionary turnover and overlapping variances of sex-biased gene expression patterns defy a simple binary classification of sexes

    Chen Xie, Sven Künzel, Diethard Tautz
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    1. Cell Biology
    2. Genetics and Genomics

    Pyruvate and Related Energetic Metabolites Modulate Resilience Against High Genetic Risk for Glaucoma

    Keva Li, Nicholas Tolman ... UK Biobank Eye and Vision Consortium
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Identification of novel microcephaly-linked protein ABBA that mediates cortical progenitor cell division and corticogenesis through NEDD9-RhoA

    Aurelie Carabalona, Henna Kallo ... Claudio Rivera
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Compelling
    1. Developmental Biology

    Numb provides a fail-safe mechanism for intestinal stem cell self-renewal in adult Drosophila midgut

    Mengjie Li, Aiguo Tian, Jin Jiang
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Uncovering the electrical synapse proteome in retinal neurons via in vivo proximity labeling

    Stephan Tetenborg, Eyad Shihabeddin ... John O’Brien
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Evolutionary Biology

    Evidence for deliberate burial of the dead by Homo naledi

    Lee R Berger, Tebogo Makhubela ... John Hawks
    Revised
    Reviewed Preprint v2
    Updated
    • Landmark
    • Convincing
    • Incomplete
    1. Developmental Biology

    3D reconstruction of neuronal allometry and neuromuscular projections in asexual planarians using expansion tiling light sheet microscopy

    Jing Lu, Hao Xu ... Kai Lei
    A high-resolution, high-speed tissue imaging analysis reveals how neural and muscular tissues coordinate during planarian growth and regeneration.
    1. Genetics and Genomics

    Dimeric R25CPTH(1–34) activates the parathyroid hormone-1 receptor in vitro and stimulates bone formation in osteoporotic female mice

    Minsoo Noh, Xiangguo Che ... Sihoon Lee
    A novel mutant, R25CPTH, derived from a hypoparathyroidism patient, can form a dimer that activates PTH1R and enhances bone formation in female mice similar to PTH despite altered molecular properties.
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Magazine

  1. Science Under Threat in the United States: Campaigning for science and scientists

    Adriana Bankston

  2. Science Under Threat in the United States: How to make science more efficient

    Stuart Buck
    1. Neuroscience

    Memory: Integrating past experiences

    Thomas MW Leir, Matthew PH Gardner
  4. Scientists at a Stand Up For Science rally

    Science Under Threat in the US

    Edited by Peter A Rodgers

  5. Science Under Threat in the United States: Research turns hope into reality

    Anna C Greene, Casey S Greene

  6. Science Under Threat in the United States: The impact on undergraduate students

    Reenie Tian, Kamna Kalkunte ... Mayank Chugh

  7. Science Under Threat in the United States: How scientists and institutions should respond

    Ran Blekhman
  8. See more Magazine articles

Research categories

  1. Biochemistry and Chemical Biology
  2. Cancer Biology
  3. Cell Biology
  4. Chromosomes and Gene Expression
  5. Computational and Systems Biology
  6. Developmental Biology
  7. Ecology
  8. Epidemiology and Global Health
  9. Evolutionary Biology
  10. Genetics and Genomics
  11. Immunology and Inflammation
  12. Medicine
  13. Microbiology and Infectious Disease
  14. Neuroscience
  15. Physics of Living Systems
  16. Plant Biology
  17. Stem Cells and Regenerative Medicine
  18. Structural Biology and Molecular Biophysics
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